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INTERMITTENT FASTING: Strengthen Gut Health, Reduce Inflammation, and Optimize Metabolism

  • Mar 4
  • 4 min read

Have you heard about the benefits of intermittent fasting but wonder how it affects your body—especially your gut health? Studies show that fasting can not only support weight loss but also strengthen gut flora, preserve muscle mass, reduce inflammation, and improve energy levels. By giving your digestive system a break, you create optimal conditions for beneficial gut bacteria, increased butyrate production, and a stronger gut barrier.


In this article, we explore how intermittent fasting can balance blood sugar, reduce oxidative stress, and boost your energy—all while promoting a healthy gut and overall well-being. ✨


Doctor Berit Nordstrand in front of a table of food, in a lavender field


Intermittent Fasting: More Than Just a Diet Pattern

Intermittent fasting (IF) has been a key part of religious and cultural traditions for centuries. Today, it is widely recognized as an effective tool for weight management and health improvement. But why does fasting offer so many health benefits, and how does it impact gut health?

Research shows that fasting helps balance energy consumption, enhances brain function, and supports cellular health. By alternating between periods of energy deprivation (fasting and activity) and energy intake (meals and rest), you can optimize metabolism, reduce inflammation, and improve gut flora. Let's dive deeper into how intermittent fasting can support a healthier body and a longer life.


Different Methods of Intermittent Fasting

Intermittent fasting is not about what you eat but when and how often you eat. Several fasting methods exist:

  • Time-Restricted Eating (TRE) – Eating within a 6-8 hour window and fasting for 16-18 hours.

  • 5:2 Diet – Eating normally for 5 days and reducing calorie intake (500-700 kcal) for 2 days.

  • Alternate-Day Fasting (ADF) – Alternating between fasting and eating days.


The key is to find a rhythm that works for you while avoiding eating late at night.


Why Fast? The Key Lies in the Body’s Natural Adaptations

Throughout evolution, humans have experienced periods of food scarcity. Our ancestors had to hunt or gather food, and the body developed mechanisms to survive using stored energy during fasting periods. Modern eating habits—three main meals plus snacks—are relatively new in human history and can lead to overconsumption, obesity, and metabolic imbalances.

When you fast, several positive changes occur in the body:

  1. Improved Metabolism and Fat Burning

    After about 12 hours of fasting, the liver depletes its glycogen stores, prompting the body to burn fat for energy. This produces ketones, an energy source that the brain and muscles thrive on.

  2. Reduced Inflammation

    Fasting switches off pro-inflammatory mechanisms in the body and enhances natural repair processes. Less inflammation leads to better gut health, joint health, and a more resilient aging process.

  3. Enhanced Gut Health

    Fasting alters gut flora by:

    1. Promoting the growth of beneficial gut bacteria.

    2. Reducing harmful bacteria that thrive on constant food intake.

    3. Supporting the production of butyrate, a short-chain fatty acid that strengthens the gut barrier and lowers inflammation.

  4. Boosted Brain Health and Stress Resistance

    Ketones enhance brain function, improve memory, and may help protect against neurodegenerative diseases like Alzheimer’s. Fasting also activates sirtuins—longevity genes that code for enzymes that protect cells from aging.

  5. Increased Insulin Sensitivity and Blood Sugar Control

    Pausing food intake improves insulin response, potentially preventing insulin resistance and metabolic syndrome.


How to Get Started with Intermittent Fasting

🚀 Start gradually: Begin with a 12-hour fast and slowly extend to 14-16 hours.

🍽 Choose nutrient-dense meals: Prioritize protein, healthy fats, vegetables, and fermented foods.

💧 Stay hydrated: Water, herbal tea, and black coffee can help curb hunger.

⏰ Stick to consistent meal times: Your body thrives on rhythm—keep your eating window stable.

🛌 Avoid late-night eating: Eating close to bedtime can disrupt sleep and digestion.




The GØT App – Your Guide to Intermittent Fasting!

Set up your eating window in the app and gain full control over when you eat. Perfect for those who want to make fasting easier—especially for beginners! Learn more about the app here.


Hånd som holder mobil og viser spisevindu funksjon i GØT-appen

A Gift to Your Body

Intermittent fasting provides valuable breaks for your body to repair, rejuvenate, and optimize metabolism. It reduces inflammation, supports gut health, aids in weight loss, and boosts brain function.

By combining fasting with nutrient-rich foods and a balanced lifestyle, you can lay the foundation for a long and healthy life. 🌱


Is Intermittent Fasting for Everyone? Important Considerations and Potential Risks

While intermittent fasting offers many health benefits, it’s not suitable for everyone. Some studies suggest fasting may have side effects and should be avoided by specific groups.

Intermittent fasting is not recommended for:

  • Pregnant and breastfeeding women

  • Individuals with hormonal imbalances

  • Premenopausal women

  • Children

  • Elderly individuals with frailty

  • People with type 1 diabetes, dementia, or a history of eating disorders or food insecurity

Potential side effects include hypoglycemia, dizziness, and weakness, especially for those taking blood sugar-lowering medications. It’s crucial to listen to your body and adjust your fasting routine based on individual needs.



References:

  • Sun, Ming-Li, et al. Intermittent fasting and health outcomes: an umbrella review of systematic reviews and meta-analyses of randomized controlled trials. EClinicalMedicine 70 (2024).

  • Vasim, Izzah, Chaudry N. Majeed, and Mark D. DeBoer. Intermittent fasting and metabolic health. Nutrients 14.3 (2022): 631.

  • Kapogiannis, Dimitrios, et al. Brain responses to intermittent fasting and the healthy living diet in older adults. Cell Metabolism 36.8 (2024): 1668-1678.

  • Korenfeld, Noga, et al. Repeated fasting events sensitize enhancers, transcription factor activity, and gene expression to support augmented ketogenesis. Nucleic Acids Research 53.1 (2025): gkae1161.

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